A know-it-all gets Ms. Frizzle's (Lily Tomlin) class lost in outer space.
Ms. Frizzle's students explore Arnold's digestive system after he accidentally swallows his miniaturised classmates.
While Ralphie hosts a TV broadcast from his sickbed, his classmates seek to discover the cause of his illness.
Establishing a connection between a soggy shoe and a tuna sandwich leads to an ocean field trip.
Ms. Frizzle's miniaturised class becomes a mechanical frog so it can hop along in search of Wanda's missing pet.
On "Accidental Science Project Day," the class takes a close look at what's rotting in an abandoned lot.
Lily Tomlin
Ms. Valerie Frizzle
Danny Tamberelli
Arnold Matthew Perlstein
Daniel DeSanto
Carlos Ramon
Tara Meyer
Dorothy Ann
Erica Luttrell
Keesha Franklin