When ex-blues musician Lazarus (Samuel L. Jackson) finds the town nymphomaniac Rae (Christina Ricci) left for dead on the side of the road, he vows to nurse her back to health... and cure her of her wickedness. Until then, she’ll be chained to the immovable radiator in his home. But Lazarus has demons of his own: his wife just left him for his own brother. While Lazarus and Rae struggle to fix their broken lives, the situation threatens to explode as Rae's boyfriend Ronnie (Justin Timberlake) — a roughneck soldier just back from Iraq — comes searching for his missing lover.