Pietro Zinni is in jail once again, and this time he has the whole gang in there with him, forcing them to plan the ultimate escape in order to complete the toughest job yet. The objective is no longer a hunt for smart-drugs in this third and final chapter of the I Can Quit Whenever I Want saga: now the enemy is Walter Mercurio, another former university researcher who executed a massacre by releasing nerve gas during an important award ceremony at the university. Now the gang has no one to count on but themselves: these researchers will have to go against everything and everyone if they want to complete this last mission which is bound to be the greatest one of all.