A CIA black ops recruit, Mitch Rapp (O'Brien), is devastated by the loss of his girlfriend to a terrorist attack. CIA Deputy Director Irene Kennedy (Lathan) assigns Stan Hurley (Keaton) to train a grief-stricken but highly motivated Rapp how to thwart terrorist operations and hunt the perpetrators. Together they investigate a wave of apparently random attacks on military and civilian targets and discover a pattern in the violence that leads them to a joint mission with a lethal Turkish agent (Negar) to stop a mysterious operative (Kitsch) intent on starting a world war in the Middle East.