Chuck Lorre (“Two and a Half Men”) & Bill Prady (“Gilmore Girls”) co-created this new comedy about a pair of brilliant physicists – roommates Leonard (Johnny Galecki – “Roseanne”) and Sheldon (Jim Parsons – “Judging Amy,” “Garden State”) – who understand how the universe works but have no clue about how to interact with people, especially women.  All this begins to change when a free-spirited beauty named Penny (Kaley Cuoco, “8 Simple Rules… for Dating My Teenage Daughter”) moves in next door. Sheldon is quite content spending his nights playing Klingon Boggle with their socially dysfunctional friends, fellow Caltech scientists Wolowitz (Simon Helberg – “Studio 60 on the Sunset Strip) and Koothrappali (Kunal Nayyar, “Huck & Holden”). However, Leonard sees in Penny a whole new universe of possibilities ... including love.