After a plane crash, a young therapist, Claire (Anne Hathaway), is assigned by her mentor (Andre Braugher) to counsel the flight's five survivors. When they share their recollections of the incident - which some say include an explosion that the airline claims never happened - Claire is intrigued by Eric (Patrick Wilson), the most secretive of the passengers. Just as Claire's professional relationship with Eric - despite her better judgment - blossoms into a romance, the survivors begin to disappear mysteriously, one by one. Claire suspects that Eric may hold all the answers and becomes determined to uncover the truth, no matter the consequences.