Jessie is a small town girl with big dreams who embarks on the adventure of a lifetime when she decides to leave behind starry nights for big city lights. Thrilled to be on her own and determined not to be intimidated by New York City, she accepts a job as a nanny and moves in with the Ross family -- dad Morgan, a famous movie director, and mom Christina, a former supermodel turned business mogul, along with their four children, Emma, Ravi, Luke and Zuri. With a whole new world of opportunities within her reach, Jessie begins to navigate young adulthood and life in the big city. She surprises herself with how much she comes to rely on the support and advice of the kids in her care. Also helping to guide her moral compass are Bertram, the family’s butler, and Tony, the building's 20-year-old doorman.