Brain Games

Kristen Bell and Dax Shepard go head-to-head in the Battle of the Sexes, a series of games designed to find out how men's and women's brains differ. Field correspondent Cara Santa Maria plays a game of "telephone" with a group in Los Angeles and mentalist Lior Suchard astonishingly reveals the names of Bell's and Shepard's first crushes. Challenges include solving a math puzzle before a gas balloon explodes.

Actor Ted Danson and special guests The Blue Man Group play along with host Keegan-Michael Key as we learn how our brains distinguish fact from fiction. Games include identifying real vs. fake news headlines. Additionally, master mentalist Lior Suchard predicts who's lying when it comes to hiding a treasured object, and Danson takes a ride through the show's mental obstacle course, known as the Gauntlet.

New Orleans Saints quarterback Drew Brees puts his brain to the test with a series of mental challenges exploring how people have hacked their brains and how we can train our own minds to do as we want. Games include Draft Day, in which Brees tests his reaction time and cognitive flexibility, and a game of hand-eye coordination and perception. Actress Ginnifer Goodwin makes a special appearance.

Actor Anthony Anderson and his younger "Black-ish" co-star Marsai Martin face off in a series of games with Keegan-Michael Key to explore the surprising differences between adults' and kids' brains. Challenges involve language, reflexes and reaction times, and risk-taking and mind control — all before the two co-stars face off in the Gauntlet's mental obstacle course.

Jack Black and his Tenacious D bandmate Kyle Gass join Keegan-Michael Key to learn how music affects the brain. Games and demonstrations include a round of musical mad libs, "Odd-itory" illusions and experiments that show how music can affect our perception of images, emotions and even taste. Mentalist Lior Suchard asks Black to think of any song in the world and tries to guess it correctly.

Keegan-Michael Key welcomes billionaire CEO and star of "Shark Tank" Mark Cuban to explore how business-savvy, powerful brains might be different from others, and how power can manipulate the way we think. Cuban and Key undergo a series of challenges involving split-second decision-making via rapid hiring and firing and memory mastery. Plus, actor Colin Hanks makes a special guest appearance.

Actress Rebel Wilson joins Keegan-Michael Key to explore the power of the subconscious when it comes to falling in love. Master mentalist Lior Suchard stuns Wilson by giving her details of a date she remembers — and pairs off potential partners who have a surprising thing in common — before Wilson takes on the Gauntlet, an obstacle course designed to test mental strength and agility.

Actress Tiffany Haddish and director Jordan Peele join Keegan-Michael Key to play games that show how Hollywood pros manipulate our brains to make us feel genuine emotion while watching movies. Challenges include taking a closer look at some of the bizarre tactics used to create sound effects in movies, spotting the stuntman and illuminating how filmmakers manipulate our brains with editing.