Five years ago, a fire took the life of Professor Poon, and the notebook on his research for a cancer cure called "super stem cells" disappeared without a trace. His assistant Ko Yuk (Zhang Jingchu) was escaped death thanks to security guard Chong Tin-po (Daniel Wu). After losing his wife to cancer several years ago, Tin-po entered "Sky Number One," a top-level medical facility financed by the tycoons, as a security guard. He hopes that the lab will finally find a cure for cancer, but he realizes that Ko Yuk is the only researcher that is actually trying to develop "super stem cells" to save lives. Meanwhile, her husband, "Sky Number One" president Tong Wing-cheung, is a ruthless businessman who puts money ahead of everything and will take any means necessary to get his way. Chia-chia (Joseph Chang) has brought his cancer-afflicted sister Jen (Amber Kuo) to Hong Kong in search for a cure, but they're suddenly caught in the middle of a daring robbery planned by Professor Poon's son, Poon Chi-man. To discover the truth behind his father's murder, Chi-man steals the "super stem cell" and engages in an explosive battle against Tin-po and his security team. Tin-po fights to protect the stolen medicine, and Chia-chia needs to steal the medicine to save his sister. When the two men find out that Chi-man and his team are the good guys after all, they face a moral dilemma: Should they betray Chi-man or help him defeat the tyrant that is Tong Wing-cheung? Prepare for an all-out war that will rock the city!
